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our Publications

2024

Developing enhanced immunotherapy using NKG2A knockout human pluripotent stem cell-derived NK cells

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Staggered immunization with mRNA vaccines encoding SARS-CoV-2 polymerase or spike antigens broadens the T cell epitope repertoire

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Targeting ABCG1 and SREBP-2 mediated cholesterol homeostasis ameliorates Zika virus-induced ocular pathology

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Envelope protein-specific B cell receptors direct lentiviral vector tropism in vivo

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Mpox Virus and its ocular surface manifestations

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2023

Low complexity domains of the nucleocapsid protein of SARS-CoV-2 form amyloid fibrils

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Innate immune pathway modulator screen identifies STING pathway activation as a strategy to inhibit multiple families of arbo and respiratory viruses.

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Differential Susceptibility of Ex Vivo Primary Glioblastoma Tumors to Oncolytic Effect of Modified Zika Virus.

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A ketogenic diet can mitigate SARS-CoV-2 induced systemic reprogramming and inflammation

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Differential Susceptibility of Fetal Retinal Pigment Epithelial Cells, hiPSC- Retinal Stem Cells, and Retinal Organoids to Zika Virus Infection

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2022

Replication-Deficient Zika Vector-Based Vaccine Provides Maternal and Fetal Protection in Mouse      Model.

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Development of off-the-shelf hematopoietic stem cell-engineered invariant natural killer T cells for COVID-19 therapeutic intervention. 

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Hippo signaling pathway activation during SARS-CoV-2 infection contributes to host antiviral response.

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Compound screen identifies the small molecule Q34 as an inhibitor of SARS-CoV-2 infection. 

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Longitudinal Evaluation of Antibody Persistence in Mother-Infant Dyads After Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Pregnancy.

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 A CRISPR Activation Screen Identifies an Atypical Rho GTPase That Enhances Zika Viral Entry. 

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ORAI1 Limits SARS-CoV-2 Infection by Regulating Tonic Type I IFN Signaling.
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The systemic inflammatory landscape of COVID-19 in pregnancy: Extensive serum proteomic profiling of mother-infant dyads with in utero SARS-CoV-2.

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SARS-CoV-2 and its beta variant of concern infect human conjunctival epithelial cells and induce differential antiviral innate immune response. 

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2021

A systems-level study reveals host-targeted repurposable drugs against SARS-CoV-2 infection.

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Deleterious Effects of SARS-CoV-2 Infection on Human Pancreatic Cells. 

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SARS-CoV-2 infection of primary human lung epithelium for COVID-19 modeling and drug discovery.

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Antiviral drug screen identifies DNA-damage response inhibitor as potent blocker of SARS-CoV-2 replication.

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SARS-CoV-2 infection rewires host cell metabolism and is potentially susceptible to mTORC1 inhibition.

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ApoE-Isoform-Dependent SARS-CoV-2 Neurotropism and Cellular Response. 

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2020

Hippo Signaling Pathway Has a Critical Role in Zika Virus Replication and in the Pathogenesis of  Neuroinflammation.

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Zika Virus Mucosal Infection Provides Protective Immunity 

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